KOMPOSISI KIMIA, AKTIVITAS ANTIOKSIDAN DAN ANTIBAKTERI MINYAK ATSIRI AKAR WANGI (Vetiveria zizanoides L)

Authors

  • Diki Prayugo Wibowo Sekolah Tinggi Farmasi Indonesia
  • Diah Lia Aulifa Sekolah Tinggi Farmasi Indonesia

DOI:

https://doi.org/10.52434/jfb.v10i2.655

Abstract

Penelitian ini bertujuan untuk mengidentifikasi komponen senyawa dan mengetahui aktivitas antioksidan, antimikroba minyak atsiri Akar wangi (Vetiveria zizanoides. L). Minyak atsiri diperoleh dengan cara destilasi uap air dianalisis menggunakan kromatografi gas-spektrometri massa (KG-SM), aktivitas antioksidan ditentukan dengan metode DPPH serta aktivitas antibakteri ditentukan dengan metode mikrodilusi. Hasil analisis kromatografi gas-spektrometri massa (KG-SM) menunjukan adanya 43 senyawa dengan kandungan utama yaitu sikloisolongifolena (8,27%), 6-Isopropenil-4,8A-Dimetil-3,5,6,7,8,8A-Hexahidrol-1H-Naf (7,20%), delta cadinena (6,29%), aromedenedradiene (5,98%) dan alfa amorpena (5,45%). Aktivitas antioksidan menunjukkan bahwa minyak atsiri memiliki aktivitas antioksidan dengan IC50 0,515 μg. mL−1. Aktivitas antibakteri menunjukkan aktivitas terhadap bakteri uji Gram positif dan bakteri Gram negativ dengan konsentrasi hambat minimum minyak atsiri berkisar dari 62, 50 μg. mL−1 hingga 4000 μg. mL−1. Kandungan minyak atsiri dari tanaman akar wangi direkomendasikan untuk aktivitas antioksidan dan antibakteri. Kata kunci: Antioksidan, antibakteri, komposisi kimia, akar wangi (Vetiveria zizanoides)

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Published

2019-11-14

Issue

Vol. 10 No. 2 (2019): Jurnal Ilmiah Farmako Bahari

Section

Research Article

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