FORMULATION AND PHYSICAL PROPERTIES TEST OF NANO CREAM PREPARATION PURIFIED EXTRACT OF KENIKIR LEAF (ETDK) AND TAMPOI FRUIT PEEL EXTRACT (EKBT)

Ika Ristia Rahman, Sulastri Herdaningsih

Abstrak


This research has been conducted under the title “formulation and physical properties test of nano cream preparations purified extract of Kenikir leaf (ETDK) and Tampoi fruit peel extract (EKBT)”. This study has formulated a nano cream with a purified extract of Kenikir leaf (ETDK), Tampoi fruit peel extract (EKBT), and a combination of ETDK and EKBT. This study aims to determine the purified extract of Kenikir leaves. The purified extract of Tampoi fruit peel can be formulated as nano cream preparations and to determine the physical parameters (organoleptic test, homogeneity, pH, type of nano cream, spreadability, adhesion, and particle size) for the result of the nano cream. The results of the organoleptic test were described and the physical properties of the nano cream were analyzed by using Excel application. Organoleptic testing of the combination of ETDK and EKBT nano cream formula gave a reddish-white color with an aqueous consistency. The ETDK nano cream formula gave a white bone colour with a watery consistency. In contrast, the nano cream formula with EKBT gave a brownish white colour with a watery consistency. It gives a distinctive smell of extract. The third test of nano cream formulas showed that the physical properties of this nano cream preparation met the standard requirements for physical tests. Test the physical properties that meet the pH requirements, type of nano cream, spreadability, adhesion, and particle size, and all three formulas produced an average particle of less than 300nm.

 


Kata Kunci


kenikir leaf, nano cream, purified extract, tampoi fruit peel.

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Referensi


Andarwulan N, Kurniasih D, Apriady RA, Rahmat H, Roto AV, Bolling BW. Polyphenols, carotenoids, and ascorbic acid in underutilized medicinal vegetables. J Funct Foods [Internet]. 2012;4(1):339–47. Available from: http://dx.doi.org/10.1016/j.jff.2012.01.003

Cheng SH, Khoo HE, Ismail A, Abdul-Hamid A, Barakatun-Nisak MY. Influence of extraction solvents on Cosmos caudatus leaf antioxidant properties. Iran J Sci Technol Trans A Sci. 2016;40(1):51–8.

Whenny, Rusli Rolan RL. Aktivitas tabir surya ekstrak daun cempedak (Artocarpus Champeden Spreng). J Sains dan Kesehat. 2015;1(4):154–8.

Abu Bakar MF, Ahmad NE, Karim FA, Saib S. Phytochemicals and antioxidative properties of borneo indigenous liposu (Baccaurea lanceolata) and tampoi (Baccaurea macrocarpa) fruits. Antioxidants. 2014;

Tirtana E, Idiawati N, Warsidah, Jayuska A. ISSN 2303-1077. Analisa proksimat, uji fitokimia dan aktivitas antioksidan pada buah tampoi (Baccaurea macrocarpa). J Kim Khatulis. 2013;2(1):42–5.

Novitaria B, Alimuddin AH, Destiarti L. Isolasi dan karakterisasi golongan senyawa fenolik dari kulit batang tampoi (Baccaurea macrocarpa). J Kaji Komun. 2016;5(2):27–32.

Erwin E, Pusparohmana WR, Sari IP, Hairani R, Usman U. Phytochemical and antioxidant activity evaluation of the bark of Tampoi (Baccaurea macrocarpa) F1000Research. 2018;7:1–9.

Erwin E, Pusparohmana WR, Sari IP, Hairani R, Usman U. GC-MS profiling and DPPH radical scavenging activity of the bark of Tampoi (Baccaurea macrocarpa). F1000Research. 2019;7:1977.

Yunus R, Alimuddin HA, Ardiningsih P. Uji aktivitas antibakteri ekstrak kulit buah tampoi (Baccaurea Macrocarpa) terhadap bakteri escherichia coli dan staphylococcus aureus. J Kaji Komun. 2014;3(3):19–24.

Hanutami B, Budiman A. Penggunaan Teknologi Nano Pada Formulasi Obat Herbal. Farmaka. 2017;15:29–39.

Zainol NA, Ming TS, Darwis Y. Development and characterization of cinnamon leaf oil nanocream for topical application. Indian J Pharm Sci. 2015;77(4):422–33.

Sonje A, Thube R, Parmar V, Kumari G, Deshpande P. A review on penetration enhancer for semisolids. Asian J Pharm Res Dev [Internet]. 2013;1(5):94–107. Available from: www.ajprd.com 93

Jusnita N, Tridharma WS. Karakterisasi nanoemulsi ekstrak daun kelor (Moringa oleifera Lamk.). J Sains Farm Klin. 2019;

Hospita K, Berefek LY. Formulasi dan uji stabilitas sediaan gel ekstrak terpurifikasi daun paliasa (Kleinhovia Hospita L.) yang berefek antioksidan. Pharmacon. 2017;6(3):157–69.

Abdulkarim MF, Abdullah GZ, Chitneni M, Mahdi ES, Yam MF, Faisal A, et al. Stability studies of nano-cream containing piroxicam. Int J Drug Deliv. 2010;2(4):333–9.

Juniatik M, Hidayati K, Wulandari FP, Pangestuti N, Munawaroh N, Martien R, et al. Formulation of nanoemulsion mouthwash combination of lemongrass oil (Cymbopogon citratus) and kaffir lime oil (Citrus Hystrix) for anticandidiasis against candida albicans ATCC 10231. Tradit Med J. 2017;22(1):7–15.

Al-Edresi S, Baie S. In-vitro and in-vivo evaluation of a photo-protective kojic dipalmitate loaded into nano-creams. Asian J Pharm Sci. 2010;5(6):251–65.

Nurjannah F. Pengaruh pelarut puriikasi terhadap kadar fenolik total ekstrak biji kopi hijau arabika (Coffe arabica L.). Skripsi. 2020;(Agustus):Universitas Nadi waluyo, Semarang.

Januarti IB, Wijayanti R, Wahyuningsih S, Nisa Z. Potensi ekstrak terpurifikasi daun sirih merah (Piper crocatum Ruiz &Pav) sebagai antioksidan dan antibakteri. JPSCR J Pharm Sci Clin Res. 2019;4(2):60.

Garg A, Aggarwal D, Garg S, Singla AK. Spreading of semisolid formulations: An update. Pharm Technol North Am. 2002 Sep 1;26:84–105.

Indratmoko S, Nurmayadah H, Nurwahidah AT. Pengembangan Formula krim nanosqualene cream formula development with tween 80 and PEG 400 combinations. Borneo J Phamascientech. 2019;03(02):160–8.

Destiyana OY, Hajrah, Rijai L. Formulasi nanoemulsi kombinasi ekstrak bunga mawar (Rosa damascena Mill.) dan ekstrak umbi bengkuang (Pachyrhizus erosus L.) menggunakan minyak pembawa virgin coconut oil (VCO). Proceeding Mulawarman Pharm Conf [Internet]. 2018 Dec 31;8(1 SE-Articles). Available from: https://prosiding.farmasi.unmul.ac.id/index.php/mpc/article/view/331

Hermanto VC. Pembuatan nanokrim kojic acid dipalitate dengan kombinasi surfaktan tween 80 dan kosurfaktan propilen glikol 400 menggunakan mixer. Skripsi. 2016;Universitas Sanata Darma, Yogyakarta.

Lee SJ, McClements DJ. Fabrication of protein-stabilized nanoemulsions using a combined homogenization and amphiphilic solvent dissolution/evaporation approach. Food Hydrocoll [Internet]. 2010;24(6):560–9. Available from: https://www.sciencedirect.com/science/article/pii/S0268005X10000238




DOI: http://dx.doi.org/10.52434/jfb.v12i2.1218

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