Fitokimia, Kemotaksonomi, dan Sifat Biologis Metabolit Sekunder dari Tanaman Jambu Air
DOI:
https://doi.org/10.52434/npcb.v1i2.43321Keywords:
aktivitas biologis , fitokimia, syzygium aqueum, syzygium malaccense, syzygium samarangenseAbstract
Artikel ini merangkum komposisi fitokimia, kemotaksonomi, dan aktivitas biologis tiga spesies utama jambu air, yaitu Syzygium aqueum, Syzygium malaccense, dan Syzygium samarangense, berdasarkan publikasi ilmiah yang tervalidasi. Kajian menunjukkan bahwa ketiga spesies tersebut kaya akan flavonoid, senyawa fenolik, antosianin, terpenoid, kalkon, minyak volatil, dan sterol. Flavonoid dan turunan fenolik merupakan kelompok metabolit yang paling dominan, sedangkan α-pinene, β-selinene, α-terpineol, dan cyanidin-3-glucoside merupakan senyawa yang paling konsisten dilaporkan pada lebih dari satu spesies dan berpotensi digunakan sebagai penanda kemotaksonomi. Berbagai studi juga menunjukkan aktivitas antioksidan, antidiabetes, antimikroba, antiinflamasi, hepatoprotektif, sitotoksik, dan imunomodulator yang berkaitan dengan kandungan polifenol dan terpenoidnya. Secara keseluruhan, genus Syzygium memiliki prospek kuat sebagai sumber senyawa bioaktif untuk pengembangan obat dan produk kesehatan berbasis bahan alam.
References
Arumugam, B., Manaharan, T., Heng, C. K., Kuppusamy, U. R., & Palanisamy, U. D. (2014). Antioxidant and antiglycemic potentials of a standardized extract of Syzygium malaccense. LWT, 59(2P1), 707–712. https://doi.org/10.1016/j.lwt.2014.06.041
Arumugam, B., Palanisamy, U. D., Chua, K. H., & Kuppusamy, U. R. (2016). Potential antihyperglycaemic effect of myricetin derivatives from Syzygium malaccense. Journal of Functional Foods, 22, 325–336. https://doi.org/10.1016/j.jff.2016.01.038
Aung, E. E., Kristanti, A. N., Aminah, N. S., Takaya, Y., & Ramadhan, R. (2020). Plant description, phytochemical constituents and bioactivities of Syzygium genus: A review. In Open Chemistry (Vol. 18, Issue 1, pp. 1256–1281). https://doi.org/10.1515/chem-2020-0175
Batista, Â. G., da Silva, J. K., Betim Cazarin, C. B., Biasoto, A. C. T., Sawaya, A. C. H. F., Prado, M. A., & Maróstica Júnior, M. R. (2017). Red-jambo (Syzygium malaccense): Bioactive compounds in fruits and leaves. LWT, 76, 284–291. https://doi.org/10.1016/j.lwt.2016.05.013
Hariyati, T., Jekti, D. S. D., & Andayani, Y. (2015). Pengaruh ekstrak etanol daun jambu air (Syzygium aqueum) terhadap bakteri isolat klinis. Jurnal Penelitian Pendidikan IPA, 1(2). https://doi.org/10.29303/jppipa.v1i2.16
Hu, Y. K., Wang, L., Li, Y. Y., Li, M. J., Xu, W., Zhao, Y., Li, F., & Zhao, Y. (2018). Five new triterpenoids from Syzygium samarangense (Bl.) Merr. et Perry. Phytochemistry Letters, 25, 147–151. https://doi.org/10.1016/j.phytol.2018.04.018
Hu, Y. K., Wang, L., Wang, J. H., Li, M. J., Li, F., Yang, J., & Zhao, Y. (2021). Resorcinol derivatives with α-glucosidase inhibitory activities from Syzygium samarangense. Natural Product Research, 35(24), 1–6. https://doi.org/10.1080/14786419.2020.1805606
Hu, Y. K., Wang, L., Zhao, Y., Liu, J. P., Wang, J. H., & Zhao, Y. (2020). Two New Oleanane Triterpenoids from Syzygium samarangense. Chemistry of Natural Compounds, 56(4), 692–695. https://doi.org/10.1007/s10600-020-03121-z
Karioti, A., Skaltsa, H., & Gbolade, A. A. (2007). Analysis of the leaf oil of syzygium malaccense merr. et perry from nigeria. Journal of Essential Oil Research, 19(4), 313–315. https://doi.org/10.1080/10412905.2007.9699290
Kim, Y. J., Kim, H. C., Ko, H., Amor, E. C., Lee, J. W., & Yang, H. O. (2012). Inhibitory effects of aurentiacin from Syzygium samarangense on lipopolysaccharide-induced inflammatory response in mouse macrophages. Food and Chemical Toxicology, 50(3–4), 1027–1035. https://doi.org/10.1016/j.fct.2011.11.050
Kuo, Y. C., Yang, L. M., & Lin, L. C. (2004). Isolation and immunomodulatory effect of flavonoids from Syzygium samarangense. Planta Medica, 70(12), 1237–1239. https://doi.org/10.1055/s-2004-835859
Lim, T. K. (2012). Edible medicinal and non-medicinal plants. In Edible Medicinal and Non-Medicinal Plants. https://doi.org/10.1007/978-90-481-8661-7
Mahmoud, M. F., Abdelaal, S., Mohammed, H. O., El-Shazly, A. M., Daoud, R., Abdelfattah, M. A. O., & Sobeh, M. (2021). Syzygium aqueum (Burm.f.) Alston Prevents Streptozotocin-Induced Pancreatic Beta Cells Damage via the TLR-4 Signaling Pathway. Frontiers in Pharmacology, 12, 769244. https://doi.org/10.3389/fphar.2021.769244
Manaharan, T., Appleton, D., Cheng, H. M., & Palanisamy, U. D. (2012). Flavonoids isolated from Syzygium aqueum leaf extract as potential antihyperglycaemic agents. Food Chemistry, 132(4), 1802–1807. https://doi.org/10.1016/j.foodchem.2011.11.147
Mulqie, L., Suwendar, S., Choesrina, R., & Mardliyani, D. (2021). Potensi antibakteri fraksi air daun jambu air [Eugenia aqueum (Burm. F) Alston] terhadap Staphylococcus aureus dan Escherichia coli. Jurnal Ilmiah Farmasi Farmasyifa, 4(1), 98–104. https://doi.org/10.29313/jiff.v4i1.6818
Nair, A. G. R., Krishnan, S., Ravikrishna, C., & Madhusudanan, K. P. (1999). New and rare flavonol glycosides from leaves of Syzygium samarangense. Fitoterapia, 70(2), 148–151. https://doi.org/10.1016/S0367-326X(99)00013-1
Nunes, P. C., De Souza Aquino, J., Rockenbach, I. I., & Stamford, T. L. M. (2016). Physico-chemical characterization, bioactive compounds and antioxidant activity of Malay apple [Syzygium malaccense (L.) Merr. & L.M. Perry]. PLoS ONE, 11(6), e0158134. https://doi.org/10.1371/journal.pone.0158134
Quenon, C., Hennebelle, T., Butaud, J. F., Ho, R., Samaillie, J., Neut, C., Lehartel, T., Rivière, C., Siah, A., Bonneau, N., Sahpaz, S., Anthérieu, S., Lebegue, N., Raharivelomanana, P., & Roumy, V. (2022). Antimicrobial Properties of Compounds Isolated from Syzygium malaccense (L.) Merr. and L.M. Perry and Medicinal Plants Used in French Polynesia. Life, 12(5), 733. https://doi.org/10.3390/life12050733
Sobeh, M., Braun, M. S., Krstin, S., Youssef, F. S., Ashour, M. L., & Wink, M. (2016). Chemical Profiling of the Essential Oils of Syzygium aqueum, Syzygium samarangense and Eugenia uniflora and Their Discrimination Using Chemometric Analysis. Chemistry and Biodiversity, 13(11), 1537–1549. https://doi.org/10.1002/cbdv.201600089
Sobeh, M., Petruk, G., Osman, S., El Raey, M. A., Imbimbo, P., Monti, D. M., & Wink, M. (2019). Isolation of myricitrin and 3,5-di-o-methyl gossypetin from syzygium samarangense and evaluation of their involvement in protecting keratinocytes against oxidative stress via activation of the Nrf-2 pathway. Molecules, 24(9), 1839. https://doi.org/10.3390/molecules24091839
Tarigan, C., Pramastya, H., Insanu, M., & Fidrianny, I. (2022). Syzygium samarangense: Review of phytochemical compounds and pharmacological activities. In Biointerface Research in Applied Chemistry (Vol. 12, Issue 2, pp. 2084–2107). https://doi.org/10.33263/BRIAC122.20842107
Uddin, A. B. M. N., Hossain, F., Reza, A. S. M. A., Nasrin, M. S., & Alam, A. H. M. K. (2022). Traditional uses, pharmacological activities, and phytochemical constituents of the genus Syzygium: A review. In Food Science and Nutrition (Vol. 10, Issue 6, pp. 1789–1819). https://doi.org/10.1002/fsn3.2797
Yang, J., Su, J. C., Lei, X. P., Huang, X. J., Zhang, D. M., Ye, W. C., & Wang, Y. (2018). Acylphloroglucinol derivatives from the leaves of Syzygium samarangense and their cytotoxic activities. Fitoterapia, 129, 1–6. https://doi.org/10.1016/j.fitote.2018.06.002
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