Mini Review: Fitokimia, Kemotaksonomi, Dan Sifat Biologis Metabolit Sekunder Dari Tanaman Manggis (Garcinia mangostana L.)
DOI:
https://doi.org/10.52434/npcb.v1i1.42540Keywords:
Garcinia mangostana L, kemotaksonomi, sifat biologis, sitotoksik, tanaman Manggis xanthoneAbstract
Artikel ini membahas aspek fitokimia, kematoksonomi, dan sifat biologis dari senyawa-senyawa yang diisiolasi dari Tanaman Manggis (Garcinia mangostana L.). Dari kajian fitokimia, terdapat 86 senyawa metabolit sekunder telah berhasil diisolasi dan diidentifikasi, yang meliputi xanthone, flavanoid, triterpenoid, benzofenon, bifenil, pirol, dan benzofuran. Kajian kematoksonomi memperlihatkan bahwa senyawa-senyawa pada Tanaman Manggis (Garcinia mangostana L.) juga ditemukan pada tanaman dengan satu famili, yaitu Garcinia. Senyawa yang ditemukan telah dievaluasi aktivitas biologisnya melalui berbagai sistem uji, meliputi sifat sitotoksik, antibakteri dan antijamur, antioksidan, antimalaria, topoisomerasi I dan II, antiinflamasi, HIV-1 protease dan reverse transkriptase. Hasil pengujian senyawa-senyawa metabolit sekunder Manggis memiliki potensi besar sebagai agen antikanker, antioksidan, antibakteri dan antijamur. Pengembangan masih terus dilakukan untuk memperjelas hasil kajian dalam analisis manfaat Tanaman Manggis (Garcinia mangostana L.) sebagai sumber bahan kimia yang memiliki banyak manfaat.
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