ARTICLE REVIEW: HERBS FOR COMMON COLD TREATMENT

Lifia Bogha Riswanto, Elin Yulinah Sukandar, Atun Qowiyyah

Abstract


Herbs have been widely used empirically in preventing and treating diseases, one of which is a common cold. The use of herbs obtained from previous generations that are passed down orally can inhibit its development so that knowledge about traditional medicine needs to be documented and inventoried. This article review aims to examine and find out scientific information on the use of medicinal plants in treating the common cold. The research method used is a literature study obtained both offline and online such as books and original research articles published in SINTA accredited national journals and reputable international journals that have been published in the last 10 years. The results show that from the various plants used empirically, preclinical tests have been carried out. A total of 196 plants have been used empirically to treat the common cold, 5 plants have been tested for expectorant activity, 2 plants have been tested for antitussive activity, 3 plants have been tested for antipyretic activity, 3 plants have been tested for analgesic activity and 1 plant has been tested for anti-allergic activity. From several plants that have been tested for their activity, there are a total of 10 plants that have been tested for their acute toxicity. “Meniran†(Phyllanthus niruri L.) was the best herb to treat the common cold because of having proven to have expectorant, antitussive, analgesic effects and has been tested for acute toxicity test.


Keywords


common cold; herbs; preclinical test; toxicity test

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References


Setyopuspito, Pramitaningastuti A. Uji efektivitas antiinflamasi ekstrak etanol daun srikaya (Annona squamosa. L) terhadap edema kaki tikus putih jantan galur wistar. JIlm Farm. 2017;13(1):8–14.

Mulyani Y, Sumarna R, Patonah. Kajian etnofarmakologi pemanfaatan tanaman obat oleh masyarakat di Kecamatan Dawuan Kabupaten Subang Provinsi Jawa Barat. J Farm Galen (Galenika J Pharmacy). 2020;6(1):37–54.

Amin M, Perawati S, Sutrisno D. Etnofarmasi pada suku anak dalam di Desa Pauh Menang Kecamatan Pamenang. J Heal Technol Med. 2020;6(1):334–44.

Hermin H, Ibrahim N, Nugrahani A. Kajian etnofarmasi etnik Bungku di Kecamatan Bungku Tengah Kabupaten Morowali Provinsi Sulawesi Tengah. J Farm Galen (Galenika J Pharmacy). 2016;2(2):76–82.

Maftuchah M, Christine P, Jamaluddin M. The effectiveness of tea tree oil and eucalyptus oil aromaterapy for toddlers with common cold. J Kebidanan. 2020;10(2):131–7.

Papas D. Principles and practice of pediatric infectious diseases. Elsevier Public Heal Emerg Collect 1st ed. 2018. p. 199–202. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152197/

Simasek M, Blandino D. Treatment of common cold. Am Fam Physician. 2007;75(4):515–20. Available from: www.aafp.org/afp

Kesehatan K, RI. Hasil utama riset kesehatan dasar 2018. 2018.

Nurlela L, Harfika M. Air rebusan belimbing wuluh sebagai antitussive dan expectorant pada ISPA. J Ilm Keperawatan. 2019;14(2):50–60.

Asridawati I, Perawati S. Studi etnofarmasi pada Suku Anak Dalam (SAD) di Desa Semambu Kecamatan Sumay Kabupaten Tebo Provinsi Jambi. J Indones. 2020;17(1):172–86. Available from: http://jurnalnasional.ump.ac.id/index.php/PHARMACY/article/view/6938

Sastroanidjojo D. Obat asli Indonesia. 1948.

Mardisiswojo S. Cabe puyang warisan nenek moyang III. Jakarta: PN BALAI PUSTAKA; 1968.

Indonesia DK. Tanaman obat Indonesia. 1985.

Departemen Kesehatan Republik Indonesia. Materia medika Indonesia. 3rd ed. Jakarta; 1979. p. 15.

Islami M, Ibrahim N, Nugrahani A. Studi etnofarmasi suku Kaili Moma di Kecamatan Kulawi, Kabupaten Sigi, Provinsi Sulawesi Tengah. J Farm Galen (Galenika J Pharmacy). 2017;3(1):27–33.

Chevallier A. Encyclopedia of herbal medicine. In: 550 Herbs and Remedies for Common Ailments. 3rd ed. DK; 2016. 118, 157, 185 p.

Achmad S, Hakim E, Makmur L, Syah Y, Juliawaty L, Mujahidin D. Ilmu kimia dan kegunaan tumbuh-tumbuhan obat Indonesia. Ed 1st, editor. ITB; 2011.

Kurniati NF, Suwandi DW, Yuniati S. Aktivitas mukolitik kombinasi ekstrak etanol daun kemangi dan ekstrak etanol daun sirih merah. Tradit Med J. 2018;5(1):7–13.

Nerdy N, Manurung K. Mucolytic activity of roselle (Hibiscus sabdariffa L.) Calyces extract on cow intestinal mucus. J Kedokt Hewan - Indones J Vet Sci. 2018;12(2):43–6.

Pakadang S, Sinala S, Salasa A, Ratnah S, Rosmala Dewi S, Hilaria M. Potential of miana leaf extract as expectorant (profile place of growing, antioxidant, sputum contaminants, antibacterial, MIC, MKC expectorant). Maj Obat Tradis. 2020;25(2):94.

Nurrochmad A, W G. Aktivitas antitusif dan ekspektoran ekstrak etanol , fraksi polar-semi polar herba meniran (Phyllanthus niruri L.) pada marmut (Cavia porcellus). J Farm Indones. 2017;14(2):118–24.

Amponsaa Brobbey, A Kwarley Quartey A, Otuo-Serebour S, Ayensu I. Determination of the antimicrobial and antitussive activities of the leaves of solanum torvum. Planta Med. 2018;18(1):S1–381.

Andriyanto A, Isriyanthi N, Sastra E, Arif R, Mustika A, Manalu W. Aktivitas antipiretik ekstrak etanol buah belimbing wuluh (Averrhoa bilimbi) pada tikus putih jantan. J Vet. 2018;18(4):597.

Malik F, Ningsi A, Bafadal M, Saktiani D, Wahyuni W. Uji efek antipiretik ekstrak etanol buah wualae (Etlingera elatior (jack) R.M. Smith) terhadap mencit jantan (Mus musculus L.) galur balb/C. Pharmauho J Farm Sains, dan Kesehat. 2018;4(1):11–3.

Rahimah S, Hendrarti W, Ramlah S. Uji aktivitas ekstrak biji selasih (Ocimum basilicum L.) dengan beberapa pelarut sebagai antipiretik pada mencit (Mus musculus). J Ilm As-Syifaa. 2015;7(2):158–63.

Alyidrus R, Ariastiwi D, Mardi Y. Ekstrak etanol daun meniran (Phyllanthus niruri L.) terhadap mencit jantan (Mus musculus) yang diinduksi asam asetat sebagai analgetik. Media Farm. 2019;15(1):51.

Sentat T, Handayani F, Indaswari E. Uji aktivitas analgetik ekstrak etanol herba sembukan (Paederia foetida L.) pada mencit putih jantan (Mus musculus) yang diinduksi dengan asam asetat. J Ilm Ibnu Sina. 2020;5(2):358–63.

Afrianti R, Yenti R, Meustika D. Analgesic activity of papaya leaf extract (Carica papaya L.) on male mice induced by Acetic Acid 1%. J Sains Farm Klin. 2014;1(1):54–60.

Kawuri W, Yudhani R, Setyawan N. Efek antihistamin ekstrak daun jambu biji (Psidium guajava) pada tikus putih (Rattus norvegicus) dengan induksi ovalbumin. Smart Med J. 2019;2(1):18.

Abrori C, Nurfadhila K, Nurus Sakinah E. Uji toksisitas akut ekstrak etanol daun kemangi diukur dari nilai LD50 dan histopatologi ginjal. Agromedicine Med Sci. 2015;5(1).

Sari F, Nurkhasanah, Bachri M. Acute toxicity test of rosella (Hibiscus sabdariffa L.) Calyx Ethanolic Extract on Sprague Dawley Rats. Tradit Med J. 2016;21(1):12–8.

Ridwan Y, Satrija F, Handharyani E. Toksisitas akut ekstrak daun miana (Coleus blumei benth) pada mencit (Mus musculus). Acta Vet Indones. 2020;8(1):55–61.

Asare G, Addo P, Bugyei K, Gyan B, Adjei S, Otu-Nyarko L. Acute toxicity studies of aqueous leaf extract of phyllanthus niruri. Interdiscip Toxicol. 2011;4(4):206–10.

Bhuvaneswari T. Studies on the physico-phytochemical properties and hepatoprotective effect of solanum torvum swartz in CCl4 induced experimental toxicity in albino rats. Int J Pharm Pharm Sci. 2012;4:4–7.

Jabbar A, Wahyuni W, Yusuf M, Helmia W, Sahidin I. Uji toksisitas akut ekstrak etanol buah wualae (Etlingera elatior (Jack) R. M. Smith) terhadap gambaran histopatologi organ jantung tikus wistar (Rattus norvegicus). Pharmauho J Farm Sains, dan Kesehat. 2020;54(3–4):291–9.

Lodhi BA, Hussain MA, Ashraf MU, Farid-Ul-Haq M, Haseeb MT, Tabassum TS review/mukolitik/uji toksistas/UT ADK (Ocimumsanctum). pd. Acute Toxicity of A Polysaccharide-based Hydrogel from Seeds of Ocimum basilicum. Cellul Chem Technol. 2020;54(3–4):291–9.

Fitriana I, Wijayanti AD, Puspa Wikan Sari R, Gagak Donny S D. Toksisitas akut ekstrak sembukan (Paederia scandens (Lour.) Merr.) pada mencit (Mus musculus L.) galur swiss. J Farm Indones. 2016;13(1):12–21.

Santi T. Uji toksisitas akut dan efek antiinflamasi ekstrak metanol dan ekstrak n-heksana daun pepaya (Carica papaya L.). Pharm Sci Res. 2015;2(2):101–14.

Enechi O, Tufon E, Ogugua V. Toxicological studies of aqueous leaf extract of mucuna pruriens on albino rats. Res J Pharmacol Pharmacodyn. 2011;3(5):253–5.




DOI: http://dx.doi.org/10.52434/jfb.v13i1.1465

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