Systematic Review: Optimalisasi Stabilitas Retinol Pada Sediaan Kosmetika

Penulis

  • Tasya Permata Shella Universitas Singaperbangsa Karawang
  • Devi Ratnasari Universitas Singaperbangsa Karawang
  • Theresia Natalie Cahyani Universitas Singaperbangsa Karawang
  • Muhammad Adit Adzkia Universitas Singaperbangsa Karawang
  • Diva Valentin Universitas Singaperbangsa Karawang
  • Ailla Az-Zahraa Universitas Singaperbangsa Karawang

DOI:

https://doi.org/10.52434/jifb.v16i1.41811

Kata Kunci:

Retinol, Stabilitas, Kosmetik, Formulasi

Abstrak

Retinol adalah bentuk aktif dan turunan generasi pertama dari vitamin A yang yang memiliki banyak manfaat untuk perawatan kulit, seperti memperbaiki tekstur kulit, merangsang pembentukan kolagen, dan mengatasi masalah penuaan serta jerawat yang membuat retinol banyak dibuat dalam sediaan kosmetika. Namun, stabilitas retinol dalam sediaan kosmetik memiliki banyak tantangan karena rentan mengalami degradasi akibat paparan faktor eksternal yang dapat memicu efek toksisitas retinol. Sehingga, review ini bertujuan untuk mengidentifikasi faktor-faktor yang dapat meningkatkan stabilitas retinol dalam sediaan kosmetik. Melalui kajian literatur dari 15 jurnal internasional dalam kurun waktu 10 tahun terakhir, ditemukan bahwa penambahan berbagai eksipien dan zat aktif lain dalam formulasi, penggunaan berbagai metode pembuatan seperti emulsi, enkapsulasi mikropartikel dan nanopartikel dengan beragam matriks, serta pemilihan kemasan yang sesuai dapat secara signifikan meningkatkan stabilitas retinol.

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Unduhan

Diterbitkan

2025-01-31

Terbitan

Vol 16 No 1 (2025): Jurnal Ilmiah Farmako Bahari

Bagian

Review Article

Lisensi

Hak Cipta (c) 2025 Jurnal Ilmiah Farmako Bahari

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