KAJIAN SISTEMATIK: OPTIMALISASI STABILITAS RETINOL PADA SEDIAAN KOSMETIKA

Authors

  • Tasya Permata Shella Universitas Singaperbangsa Karawang
  • Devi Ratnasari Universitas Singaperbangsa Karawang
  • Theresia Natalie Cahyani Universitas Singaperbangsa Karawang
  • Muhammad Adit Adzkia Universitas Singaperbangsa Karawang
  • Diva Valentin Universitas Singaperbangsa Karawang
  • Ailla Az-Zahraa Universitas Singaperbangsa Karawang

DOI:

https://doi.org/10.52434/jifb.v16i1.41811

Keywords:

formulasi, kosmetik, retinol, stabilitas

Abstract

Retinol adalah bentuk aktif dan turunan generasi pertama dari vitamin A yang yang
memiliki banyak manfaat untuk perawatan kulit, seperti memperbaiki tekstur kulit,
merangsang pembentukan kolagen, dan mengatasi masalah penuaan serta jerawat
yang membuat retinol banyak dibuat dalam sediaan kosmetika. Namun, stabilitas retinol
dalam sediaan kosmetik memiliki banyak tantangan karena rentan mengalami degradasi
akibat paparan faktor eksternal yang dapat memicu efek toksisitas retinol. Sehingga,
review ini bertujuan untuk mengidentifikasi faktor-faktor yang dapat meningkatkan
stabilitas retinol dalam sediaan kosmetik. Melalui kajian literatur dari 15 jurnal
internasional dalam kurun waktu 10 tahun terakhir, ditemukan bahwa penambahan
berbagai eksipien dan zat aktif lain dalam formulasi, penggunaan berbagai metode
pembuatan seperti emulsi, enkapsulasi mikropartikel dan nanopartikel dengan beragam
matriks, serta pemilihan kemasan yang sesuai dapat secara signifikan meningkatkan
stabilitas retinol.

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Published

2025-01-31

Issue

Vol. 16 No. 1 (2025): Jurnal Ilmiah Farmako Bahari

Section

Review Article

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